If you're driving in the sand:
Tips for towing in the sand
Keep it in 4th and don't be afraid to grab 3rd up the hills...no problems running 3500-3700 rpm even up long grades.
Load as much stuff as possible in the trailer to keep the truck weight down...
Lifting the truck doesn't cause issues BUT installing taller tires does, and with non-tow you can't afford to lose any more gear ratio...