The first 4.6 Mustangs were dogs. If it was an automatic, I can imagine the Titan beating one. They didn't call that generation Cobra the Slowbra for nothing.
By 99, they were much faster. I don't think you'd have a chance, even against an auto. My buddy has a 99 Cobra with 5 speed and there is now way the Titan would stand a chance. The weight and transmission disadvantage is just too big.