You shouldn't have any problems. Just make sure to follow the break in religiously to avoid rear end problems. That goes for any truck no matter who makes it.
Also use the gears fourth and third.
Here are pics of my 25 ft rig that weighs 5500 lbs empty an 8500 lbs with water, propane, beer and toys.
I tow up and down grades on the interstate 15, 10, and the 5 with no problem. Here are some pics from easter in Ocotillo Wells.
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2004 Titan CC: SE Off Road Edition
-Fosgate System w/DVD
-Big Tow Package
-Running Boards, Grill, Bug-guard
-Retrax Rolltop
-JBA Catback Exhaust
-K/N Dropin' w/airbox mod
-Differential Cover 05
-Donahoes 2.5 inch front
-Deavers w/ Bilsteins Back
Attitude 23 FSAK Toyhauler