That's the first time I believe I've ever heard that - I thought all Titans had primary and secondary cats. I see that Courtesy lists different part numbers for 2WD and 4WD on that part of the exhaust but I didn't think/know that it had anything to do with cats but rather working around the 4WD structures (transfer case, axles, etc).
Even if that's the case, not sure I can see the value in this unless you happen to have a set of free 4WD pipes that you want to put on your truck. You could hollow out the second set of cats if they do exist that way, but the manifold itself is the thing that cracks on these trucks.