Since I purchased my 2WD Flex Fuel 2010 Titan 9 months ago, it has never started on the first crank - it always starts on the 2nd crank. This is my "Home Depot" truck so it mostly get used for short trips. If I do drive the truck long enough to warm up, it may take 4-5 cranks before it starts. Recently the 2 cranks to start became 3-4. After replacing the relay in the IPDM, the truck began starting on the 1st crank. This was short lived, though and soon went back to 1-3 cranks before starting. Last week it would not start at all. I replaced the relay again and that worked for a day or so then it would not even crank - no response at all. I replaced the battery - no change. Everything works when you run the IPDM (Door switch 10X) self diagnostic . I bought a used IPDM and replaced it anyway, no change. No codes were showing, but I reset the ECU (5X on the Accelerator) and it started on the first crank after that. I turned it off and tried 4 more times in a row and it started on the first crank each time. The next morning I tried to crank it until the battery was almost dead and it wouldn't start. I replaced the Coolant Temp sensor - no change. The code reader now says 'Codes Found 0', but if I select 'Show Codes' it says 1/1 P0850. Upon inspecting the shift assembly I found a broken red wire coming from the manual shift button (that I have never used). I removed and replaced the shift assembly after fixing the broken wire. Once again the truck started on the first crank. It cranked successfully 3 or 4 times after that, then I almost ran the battery down trying to start it. It will crank, but will not start. I removed, disassembled, cleaned and reinstalled the ignition switch, no change. I'm pulling my hair out here and running out of options. Can anyone shed some light on this issue? The problem is not consistent, and renders the truck totally unreliable. The starter cranks strongly, and I would think if the fuel pump was bad I wouldn't be able to drive it around after it starts. What else is there? I'm wasting money and time trying possible fixes but nothing works. There is no security system, chip key or remote start. There is an aftermarket audio system that I installed myself, but it has been disconnected since I started having these issues. The battery cables are clean, there are no blown fuses or fusible links. Any insight or knowledge would be greatly appreciated.