I have an '05 and I had the following issues between 61k (just after warranty) and 75k or so:
Cracked radiatior
Leaking coolant lines
Cracked manifolds
Leaking rear axle seal
Early on, front brake rotors warped and were replaced under warranty. Without looking back, I estimate I'm out about $1,700 for the repairs above. Now, at 121k, it looks like my front differential went out; I've hardly ever used the damn 4WD and the vast majority of the miles on this truck came from daily highway commuting. If I had it to do all over again, I'd be looking at Toyota, which appears to hold itself accountable for deficiencies in their product instead of licking their chops at the thought of ancillary income from repairs.