What year? King or Crew cab?
My answer will be as if you have a '12 crew (that's what I have) yours may vary slightly (i dunno that the kings have a separate rear door tweeter)
You will be OK with the rear doors...the two drivers are close enough together to just run a short wire from the x-over to the new tweets. (or cut the factory wire and put it in there...but then you got another plug to mess with)
The dash tweeter/front door speaker is where you will need to think a little...
If you must will use the crossover that came with the speaker set, and are planning on putting the tweeters in the dash, I think it would be easiest to fish a wire down from dash tweeter to door, or vice versa depending on where you want your crossover to live.
If you don't want to do that, and feel adventurous, you'd have to find where the wires to the door and the wires to the dash are connected together, and drop the crossover in there.(they split somewhere between the head unit connector M168 and the M8 and M75 connector in the kick panels...maybe someone else knows...id bet either end.. not in the middle).
I don't like altering factory harnesses,(to the point where I cut the OEM speaker connectors off the OE speakers so as not to disturb the oe harnesses) and tend to add wires for alterations like this so it can be undone simply.
In my case, as I had purchased separate tweeters with their own high pass filter, I left the harness alone (dash and door are parallel), and just installed the HP filter in the wire at the tweeter, and dropped my door speaker tweeter level by 3db.
(I do plan to Bi-amp my front end as soon as I find an incredible deal on an amp... and will then need to run wires down from the dash tweeters to that amp.)
EDIT:
I also used a plug adapter set for the factory speaker and power connector at the HU .. so I have RCA cables from the HU to under the seats(amps there), and speaker wires from the amps back up to the speaker plug adapter.
Now that I type this.. it does sound kind of lazy... but it worked great for me.