Just like oil, power steering, and brake fluid, you should be using coolant which meets the prescribed Nissan specs for your vehicle. If you did not, you will eventually have issues. The solution is a little messy but not terribly difficult. You'll need to do a full drain and distilled water flush and drain, then refill your coolant using a vacuum refill to be sure you don't get an airlock.
Check your specs, as I'm not sure what the 2006 used. Could be Nissan Blue or Nissan Green. Flush with distilled water and replace with the proper spec. Prestone, Zerex, and others make coolant spec'd to Nissan's coolant, so you don't have to buy OEM.
If you replace your radiator, you're going to need to refill anyway.